Tag: Bioidentical hormones

CJC 1295 Ipamorelin is a combination of 2 peptides. It is a Growth Hormone releasing hormone that stimulates one side of the pituitary gland. It does this in order to produce growth hormone. Ipamorelin mimics the ghrelin and binds to the ghrelin receptor in the pituitary gland in the brain. Thus, it also acts on the pituitary gland in order to produce growth hormone. These two peptides combine to act together in order to increase HGH (human growth hormone) produced in the body. The CJC 1295/Ipamorelin combo is able to achieve this by acting in two different families of receptors. [1]

What is CJC 1295?

A synthetically produced peptide, CJC 1295 was originally made to treat diseases, but has been discovered to have performance-enhancing effects that appeal to athletes. The peptide works by increasing protein synthesis and insulin-like growth factor levels. This process enables muscle tissue to grow, thereby increasing muscle mass and function.

What Is Ipamorelin?

is a hormone secretagogue, meaning it helps excrete hormones into the bloodstream while simulating the pituitary gland to produce them. It serves other functions as well. Ipamorelin is associated with improved cognitive skills, memory, pain relief, and internal body temperature regulation along with growth and muscle development. [2]

How does CJC 1295 work?

Ipamorelin and CJC 1295 are often used together to stimulate muscle development. The combination works by increasing the blood level of hormones associated with growth. It can increase muscle mass and strength, decrease body fat, improve injury recovery time, and even improve sleep quality and cognitive function.

Research completed with healthy men and women between the ages of 21 and 61, showed that CJC-1295 had the ability to increase serum growth hormone levels by 200-1000%. In these individuals, the elevated growth hormone production and release continued for up to 6 days because CJC-1295 has a half life of about 6-8 days. This longer half-life means the body continues to produce beyond the day of injection and is thought to be a great benefit has compared to other peptides that also have similar actions. For this reason and a few more, CJC-1295 has become very effective peptide for safely increasing growth hormone levels. [3]

What are the benefits of CJC1295?

• Increased Bone Density: As we get older, our bones get brittle, that is why injuries are more common.
• Increase in muscle mass
• Strengthens the cardiovascular system: More muscle mass = higher metabolism = less body fat
• The ability to burn fat: With an increase in muscle mass allows the body’s resting metabolic rate is boosted leading to more calories burned throughout the day.
• Increased Sex drive: Sex his huge. Not being able to function properly sexually can really take a toll on your mental well-being.
• Improved Recovery and Repair from Injuries: Being on a proper bio-identical hormone replacement therapy program leads to an overall improved state of well-being. This adheres to recovery time (soreness) and acute musculoskeletal injuries.
• Strengthens Immune System: It is a tremendous benefit when you are trying to attain optimal health and that is achieved by having a strong immune system

Improves cognition and memory function-It is an improved overall benefit to the body, this includes focus and feeling mental clarity and sharpness throughout the day.

Improves Insulin Sensitivity-CJC 1295 and Ipamorelin improves insulin sensitivity thus reducing the body’s triglycerides. High blood sugars are reduced which helps burning more body fat.

Who is a good candidate for CJC 1295 / Ipamorelin?

CJC-1295 can help individuals over the age of 30 to have more energy, a faster metabolism, and stay in better shape as you age. It’s not a hormone itself, so it is a relatively safe and low-risk option when all things are considered. However, it requires a prescription and is delivered via an injection, so there are some important points to cover regarding the CJC-1295 benefits and side effects trade-offs.

What are the side effects of CJC1295 / Ipamorelin?

One of the biggest reasons why CJC-1295 is being embraced by so many in their anti-aging fight is because of the relatively low rate of side effects. Most people tolerate CJC-1295 quite well, and side effects are generally mild if present at all. The most frequent side effect was injection site reaction – usually skin complaints or mild pain at the site of injection.

Most common side effects are: Sensitivity, soreness, or pain at the injection site, Flu-like symptoms, Headache, Dizzines, Nausea, Drowsiness, Flushing, Hives or other skin reactions, Hyperactivity, Difficulty swallowing

Our Conclusion on CJC 1295 / Ipamorelin peptides:

The effects of CJC-1295 have been researched thoroughly. It is beneficial in building muscle, losing body fat, and boosting energy levels. It does all these by facilitating the production of more growth hormone for your body.

CJC-1295 is a releasing factor for growth hormone and is therefore considered a Prohibited Substance under Section S2 of the WADA Prohibited List. This substance has potential performance-enhancing effects, it is readily available, and there is reason to believe that it is being used within the bodybuilding community.

FREQUENTLY ASKED QUESTIONS ON CJC1295 / IPAMORELIN

Why combine CJC-1295 & IPAMORELIN?

CJC-1295 and Ipamorelin are typically combined in therapy because the are known to work well together. CJC-1295 takes anywhere from 1-4 hours to reach peak serum in the blood, while Ipamorelin works much quicker. Ipamorelin is cleared from the body more rapidly as it’s half life is about 2 hours. The combination of both peptides ensures a rapid onset with Ipamorelin and lasting effects with CJC-1295. These 2 peptides are incredibly specific at increasing growth hormone levels when compared to other peptides. Other peptide can increase levels of cortisol (as seen with stress, can increase hunger) but neither Ipamorelin nor CJC-1295 have an effect on other hormones which is a great advantage.

How often should you take CJC-1295?

Most prescribers direct that CJC-1295 be taken once daily, via subcutaneous injection (above the muscle, below the skin) in the stomach or abdominal region. Other prescribers recommend a “5 days a week” plan, either with skipping days every 2 or 3 days, or weekdays on, weekends off for injections. There is competing evidence as to the efficacy of these two dosing regimens, but in both cases, the effects of CJC-1295 – higher circulating levels of human growth hormone – tend to last for upwards of a week following administration and continue at that level so long as the administration continues a few times a week.

Does CJC 1295 really work?

The effects of CJC-1295 have been researched thoroughly. It is beneficial in building muscle, losing body fat, and boosting energy levels. It does all these by facilitating the production of more growth hormone for your body.

How long can you take CJC 1295?

Research has shown that administering CJC-1295 once weekly helps to increase plasma GH concentrations (2-10 times more) for a period of up to 6 days after injection. Further, it increases IGF-1 levels by 1.5 to 3 times, for a period of 9 to 11 days, with no adverse side effects.

How should CJC-1295/Ipamorelin be used?

CJC-1295/Ipamorelin is injected subcutaneously or under the skin. The injection is taken at night to mimic the natural release cycle of growth hormone.

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Hormones and Weight Loss Part 1: Estrogen Hormones

Why is it so difficult to lose weight around and during menopause?   At these times, weight gain becomes more common and feels different than weight gain at other times of life.   Pounds are easier to gain, harder to lose and show up as love handles, belly fat and/or cellulite. In addition, the usual methods of dieting and exercise don’t work anymore.  Sometimes, weight loss difficulties have nothing to do with diet and exercise.

When it comes to hormones and weight loss, things like nutritional imbalances, chronic inflammation, metabolic issues, leaky gut, toxins and even genetics can cause weight loss issues. However, for women in perimenopause and menopause, the difficulties are most likely due to hormonal imbalances.  It becomes almost impossible to lose weight. This is of course until hormones are replaced and balanced.  Hormone fluctuations in perimenopause and menopause directly impact appetite, fat storage, and metabolism.   The causes of hormonal weight gain and resistance to weight loss in menopause and perimenopause are explained below.
The first important hormone to know about is estrogen.

Changes In Estrogen Levels and Weight Loss Difficulty

One cause of weight loss difficulty around and during menopause is the changing and fluctuating of estrogen levels. The ovaries produce more estrogen relative to progesterone during this time but levels of both these hormones start to decrease dramatically.  The body will find other sources of estrogen. Since fat produces estrogen, the body will increase fat production to make more estrogen.

Avoiding Weight Gain and Estrogen Dominance

Too much estrogen (estrogen dominance) can be due to dietary issues such as excess sugar, refined carbs, alcohol and red meat, and low fiber intake.  Too many antibiotics damage the gut leading to estrogen spikes because the body can’t properly detoxify or excrete waste. Environmental toxins such as phthalates and biphenyl A mimic estrogen in the body. They bind to sites that estrogen normally does. Furthermore, excess estrogen can cause the following:

• Cellulite
• Weight gain in the hip and thigh areas
• An increase in breast size and tenderness
• Fluid retention
• PMS and Irritability
• Fibroids
• Heavy periods
• Ovarian cysts

Estrogen dominance can be controlled by limiting red meat, alcohol, and cutting way down on sugar and carbs. Getting your estrogen level evaluated and balanced by a physician specializing in bioidentical hormone replacement therapy can help alleviate these serious symptoms.  In addition, balancing estrogen has lifelong benefits for health including the following:

• Losing and maintaining weight loss
• Preventing bone breakdown
• Aiding with mineral absorption
• Keeping skin hydrated
• Helping regulate menstrual cycles.

Estrogen is also important for the health of the brain, and cardiovascular system.

Hormones and Weight Loss Part 2: How The Insulin Hormone Affects Weight Loss

During perimenopause and menopause, some women notice it becomes more difficult to lose weight and easier to gain it.   Weight is not distributed the in the body as it was in younger years.  Thus, body shape can change subtly or drastically, with love handles, abdominal, breast and arm weight appearing.  Fat in these areas is an indicator of hormonal imbalance, which, in large part, is due to the hormone insulin.

WHAT ARE THE FUCNTIONS OF INSULIN AND HOW IS IT MADE?

Insulin, produced in the pancreas, regulates the digestive system by facilitating the break down and conversion of food into energy. Another major function of insulin is to regulate and stabilize blood sugar levels.  All food eaten is broken down into proteins, nutrients, and glucose for use in metabolism.  Insulin processes glucose (the body’s key fuel source) in the bloodstream and carries it into cells to be used as fuel. Once cells have received enough glucose, any excess gets stored as fat.

INSULIN RESISTENCE & TYPE 2 DIABETES

Chronically high levels of insulin can lead to a pre-diabetic condition called insulin resistance and possibly even type 2 diabetes.  Insulin levels rise in almost all women during menopause due to the hormonal imbalance triggered by changes in estrogen and progesterone. Elevated insulin levels can also be triggered by a high sugar, high refined carbohydrate diet, excessive alcohol as well as lack of exercise, stress, high blood pressure and/or a family history of diabetes.

When a woman is insulin resistant, she is producing adequate amounts of insulin but her body is not responding to it normally. Thus, Glucose is less able to enter the cells. The pancreas detects this excess glucose and increasingly pumps out insulin to push the extra glucose into the cells. Because insulin is unable to facilitate pushing glucose into the cells, excess levels of glucose build up in the blood and get stored as fat. Because this process deprives body cells of energy, a stressful situation in created leading to craving for sweets, carbohydrates, and further weight gain.

Anyone can become insulin resistant, but as just illustrated it is more common in women during perimenopause and menopause. The best way to treat insulin resistance and begin losing weight is through lifestyle changes.  Below are a few suggestions:

1. Keep glucose levels stable by eating 5-6 mini meals/day with protein and complex carbs at each meal. Proteins and complex carbs are harder to digest and keep blood sugar and insulin levels stable.
2. Don’t skip or delay meals because this slows metabolism and will cause glucose level to drop below normal.
3. Eliminate white food such as bread, pasta, and sugar.
4. quit smoking, limit alcohol, and get 7-8 hr. sleep/night.

Other Weight Loss Services

• Medical Weight Loss LA homepage
• Bioidentical Hormone Replacement Therapy
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The Best Anti-Aging Clinic in Los Angeles

Due to the emergence of Anti-Aging Medicine, it is no longer necessary to accept the mental and physical decline associated with aging. A century ago the average life expectancy was 43 to 47. Today, life expectancy has almost doubled, due mostly to advances in medicine and technology. The rapid rate of these advances may put one in position to take advantage of cutting edge technologies in the pipeline, such as genetic engineering, stem cell transplants, therapeutic cloning, nanotechnology, and artificial organs. However, a longer life span is only desirable if living longer means living stronger, healthier, and without disabilities.

This is the premise of Anti-Aging Medicine. It is also known as

• Age Management Medicine
• Longevity Medicine
• Preventive-Regenerative Medicine
• Optimal Aging Medicine

Preventive-Regenerative Medicine is a new specialty of health care based on early detection, prevention, and reversal of the degenerative effects of aging. The primary goal is living healthier for a longer period of time.

The Anti-Aging specialty began in 1993 when twelve forward thinking physicians formed the American Academy of Anti-Aging Medicine (also known as A4M). Today, the Academy is composed of 20,000 physicians and scientists from over 100 countries. It is the fastest growing scientific society in the world. The Academy is devoted to examining scientific research pertaining to:

• Cause of illnesses
• The aging Process
• And the decline in physical and mental function as aging occurs

What are the Principles of Anti-Aging medicine?

The principals of Preventive-Regenerative Medicine are well documented in medical and scientific journals. In addition, they are based on sound and responsible medical care. While traditional medicine focuses on treating the effects of the aging process, Anti-Aging Medicine focuses on treating or preventing the causes of aging. Stated differently, traditional medicine predominately treats external symptoms that have internal causes. On the contrary, Anti-Aging Medicine addresses the internal causes in order to prevent external symptoms. The different approach may sound subtle. That being said, it can produce substantial differences in a person’s health and well-being.

What are The Modalities of Anti-Aging Medicine?

As an Anti-Aging clinic in Los Angeles, CA, you might be wondering what modalities we use. In order to deliver our anti-aging medicine, Dr. Judi Goldstone uses a combination of Bioidentical Hormone Replacement Therapy, Testosterone Treatment, Peptides and more. In addition, Dr. Goldstone’s weight loss and medical weight loss departments help people with diet needs.

Anti-Aging Clinics in Los Angeles & Holistic Health

You have to understand that the functional medicine and anti-aging models follow a holistic protocol. That means that the body is treated as a whole. On the contrary in traditional medicine, you would have to see a rheumatologist for obscure autoimmune system, a gastrologist for gut issues and so on and so forth. This presents a multitude or problems. For one, each doctor is zero’d in on one part of the body they are trained to be so-called experts in. Thus, they fail to take into account if the gastrointestinal issues are merely a symptom of the main issue or root cause. What you have is a domino effect of failing to follow best practices. If you are suffering from acid-reflux, IBS or any sort of gut ailment, the Gastroenterologists might prescribe something like Prevacid. This medication has the potential to disrupt the balance of digestive juices in your gut. Thus creating the potential that can lead to further, more serious health problems. The protocol when you have a more serious condition calls for either more prescription drugs or even surgery which compromises your system forever.

Anti-Aging & Bioidentical Hormone Replacement Therapy

When it comes to being an anti-aging clinic in Los Angeles, Bioidentical hormone replacement therapy is the meat and potatoes of what we do. Depending on your goals, needs and ailments, a proper bioidentical hormone program can change your life. By optimizing your hormone levels, you can treat energy, fatigue, chronic pain and more.

If you desire to live a longer, healthier and more productive lifestyle, call the Southern California Center For Anti-Aging today at 424.247.4962.

The Southern California Center For Anti-Aging Medicine serves patients throughout

• Los Angeles County
• Torrance
• San Pedro
• LA
• LA Metro
• Hermosa, Beach
• Carson
• Lomida
• Marina Del Rey
• Rancho
• Palos Verdes
• Manhattan Beach
• Redondo Beach

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