Tag: hormone replacement therapy

CJC 1295 Ipamorelin is a combination of 2 peptides. It is a Growth Hormone releasing hormone that stimulates one side of the pituitary gland. It does this in order to produce growth hormone. Ipamorelin mimics the ghrelin and binds to the ghrelin receptor in the pituitary gland in the brain. Thus, it also acts on the pituitary gland in order to produce growth hormone. These two peptides combine to act together in order to increase HGH (human growth hormone) produced in the body. The CJC 1295/Ipamorelin combo is able to achieve this by acting in two different families of receptors. [1]

What is CJC 1295?

A synthetically produced peptide, CJC 1295 was originally made to treat diseases, but has been discovered to have performance-enhancing effects that appeal to athletes. The peptide works by increasing protein synthesis and insulin-like growth factor levels. This process enables muscle tissue to grow, thereby increasing muscle mass and function.

What Is Ipamorelin?

is a hormone secretagogue, meaning it helps excrete hormones into the bloodstream while simulating the pituitary gland to produce them. It serves other functions as well. Ipamorelin is associated with improved cognitive skills, memory, pain relief, and internal body temperature regulation along with growth and muscle development. [2]

How does CJC 1295 work?

Ipamorelin and CJC 1295 are often used together to stimulate muscle development. The combination works by increasing the blood level of hormones associated with growth. It can increase muscle mass and strength, decrease body fat, improve injury recovery time, and even improve sleep quality and cognitive function.

Research completed with healthy men and women between the ages of 21 and 61, showed that CJC-1295 had the ability to increase serum growth hormone levels by 200-1000%. In these individuals, the elevated growth hormone production and release continued for up to 6 days because CJC-1295 has a half life of about 6-8 days. This longer half-life means the body continues to produce beyond the day of injection and is thought to be a great benefit has compared to other peptides that also have similar actions. For this reason and a few more, CJC-1295 has become very effective peptide for safely increasing growth hormone levels. [3]

What are the benefits of CJC1295?

• Increased Bone Density: As we get older, our bones get brittle, that is why injuries are more common.
• Increase in muscle mass
• Strengthens the cardiovascular system: More muscle mass = higher metabolism = less body fat
• The ability to burn fat: With an increase in muscle mass allows the body’s resting metabolic rate is boosted leading to more calories burned throughout the day.
• Increased Sex drive: Sex his huge. Not being able to function properly sexually can really take a toll on your mental well-being.
• Improved Recovery and Repair from Injuries: Being on a proper bio-identical hormone replacement therapy program leads to an overall improved state of well-being. This adheres to recovery time (soreness) and acute musculoskeletal injuries.
• Strengthens Immune System: It is a tremendous benefit when you are trying to attain optimal health and that is achieved by having a strong immune system

Improves cognition and memory function-It is an improved overall benefit to the body, this includes focus and feeling mental clarity and sharpness throughout the day.

Improves Insulin Sensitivity-CJC 1295 and Ipamorelin improves insulin sensitivity thus reducing the body’s triglycerides. High blood sugars are reduced which helps burning more body fat.

Who is a good candidate for CJC 1295 / Ipamorelin?

CJC-1295 can help individuals over the age of 30 to have more energy, a faster metabolism, and stay in better shape as you age. It’s not a hormone itself, so it is a relatively safe and low-risk option when all things are considered. However, it requires a prescription and is delivered via an injection, so there are some important points to cover regarding the CJC-1295 benefits and side effects trade-offs.

What are the side effects of CJC1295 / Ipamorelin?

One of the biggest reasons why CJC-1295 is being embraced by so many in their anti-aging fight is because of the relatively low rate of side effects. Most people tolerate CJC-1295 quite well, and side effects are generally mild if present at all. The most frequent side effect was injection site reaction – usually skin complaints or mild pain at the site of injection.

Most common side effects are: Sensitivity, soreness, or pain at the injection site, Flu-like symptoms, Headache, Dizzines, Nausea, Drowsiness, Flushing, Hives or other skin reactions, Hyperactivity, Difficulty swallowing

Our Conclusion on CJC 1295 / Ipamorelin peptides:

The effects of CJC-1295 have been researched thoroughly. It is beneficial in building muscle, losing body fat, and boosting energy levels. It does all these by facilitating the production of more growth hormone for your body.

CJC-1295 is a releasing factor for growth hormone and is therefore considered a Prohibited Substance under Section S2 of the WADA Prohibited List. This substance has potential performance-enhancing effects, it is readily available, and there is reason to believe that it is being used within the bodybuilding community.

FREQUENTLY ASKED QUESTIONS ON CJC1295 / IPAMORELIN

Why combine CJC-1295 & IPAMORELIN?

CJC-1295 and Ipamorelin are typically combined in therapy because the are known to work well together. CJC-1295 takes anywhere from 1-4 hours to reach peak serum in the blood, while Ipamorelin works much quicker. Ipamorelin is cleared from the body more rapidly as it’s half life is about 2 hours. The combination of both peptides ensures a rapid onset with Ipamorelin and lasting effects with CJC-1295. These 2 peptides are incredibly specific at increasing growth hormone levels when compared to other peptides. Other peptide can increase levels of cortisol (as seen with stress, can increase hunger) but neither Ipamorelin nor CJC-1295 have an effect on other hormones which is a great advantage.

How often should you take CJC-1295?

Most prescribers direct that CJC-1295 be taken once daily, via subcutaneous injection (above the muscle, below the skin) in the stomach or abdominal region. Other prescribers recommend a “5 days a week” plan, either with skipping days every 2 or 3 days, or weekdays on, weekends off for injections. There is competing evidence as to the efficacy of these two dosing regimens, but in both cases, the effects of CJC-1295 – higher circulating levels of human growth hormone – tend to last for upwards of a week following administration and continue at that level so long as the administration continues a few times a week.

Does CJC 1295 really work?

The effects of CJC-1295 have been researched thoroughly. It is beneficial in building muscle, losing body fat, and boosting energy levels. It does all these by facilitating the production of more growth hormone for your body.

How long can you take CJC 1295?

Research has shown that administering CJC-1295 once weekly helps to increase plasma GH concentrations (2-10 times more) for a period of up to 6 days after injection. Further, it increases IGF-1 levels by 1.5 to 3 times, for a period of 9 to 11 days, with no adverse side effects.

How should CJC-1295/Ipamorelin be used?

CJC-1295/Ipamorelin is injected subcutaneously or under the skin. The injection is taken at night to mimic the natural release cycle of growth hormone.

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How Does Human Chorionic Gonadotropin (hCG) come into play during TRT Treatment?

Several studies have found that low doses of human chorionic gonadotropin (hCG) can help to solve the testicular shrinkage caused by testosterone replacement therapy.  hCG is another hormone in the body that is mainly responsible for fertility and fetal development. In men, it can help to increase the production of testosterone and sperm.
When on testosterone replacement therapy, the body may shut off its production of testosterone. This can lead to shrinking of testicles, and a reduction in fertility. Using hCG can help to keep these things from happening. hCG is an injection that is administered by patients under the skin, (like insulin). It is very effective at treating testicular shrinkage and decreased fertility.

Potential Side Effects

As with any product you put into your body, there may be side effects with taking hCG. These include:

• Headache
• Irritability
• Restlessness
• Depression
• Fatigue
• Edema
• Pain at the site of injection
• Sensitivity at the site of the injection

What is Testosterone?

Testosterone is a hormone the body produces mainly in the testicles, which helps to maintain different processes in a man’s body. Some examples are:

• Bone density
• Fat distribution
• Muscle strength and mass
• Facial and body hair
• Red blood cell production
• Sex drive
• Sperm production

As men age, their production of testosterone gradually declines. Low testosterone, also known as hypogonadism, can be from a problem with the testicles or due to malfunction of the hypothalamus or pituitary gland in the brain. In these cases, testosterone replacement is the best option to reduce the symptoms that men can experience. Symptoms that men can experience when they have low testosterone levels include:

• Changes in sexual function–this can range from a reduction in sexual desire, fewer erections, and infertility.
• Changes in sleep–can cause insomnia
• Physical changes–many changes can occur, including an increase in body fat, reduced muscle strength, decreased bone density, swollen and tender breasts, and hair loss.
• Emotional changes – patients can also experience a decrease in motivation, self-confidence, feel sad or depressed, or have trouble remembering or concentrating.

Testosterone replacement is the current treatment for hypogonadism, and it is available in several forms. With help from a doctor, patients can decide which form or replacement will be best form them-patches and gels applied to the skin, injections, or implants.

What Are Some Side Effects of Testosterone Treatment?

Most men who undergo replacement therapy report feeling like they have more energy, a boost in sex drive, enhancement in memory, and focus. Listed below are some side effects to know of:

• Increased hematocrit and blood viscosity
• Testicular shrinkage
• Acne/skin reactions
• Reduced male fertility

Contact us today by calling and making your appointment at the Southern California Center for Anti-Aging if you are interested in finding out if you are a candidate for testosterone therapy.

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Is it possible to get older without having to experience all of the usual symptoms of aging?

We often think of the search for eternal youth beginning in the 16th century with Ponce de León. Whether the accounts were totally factual or not, it is believed that the Spanish explorer was seeking the mythical fountain of youth when he stumbled upon Florida. In fact, for as long as there have been people on the planet, there has been the desire to remain young and avoid, not just death, but the stages leading up to it.  

The saying about “nothing being certain but death and taxes”, usually attributed to Benjamin Franklin, does not seem as popular as it used to be. Perhaps that is because the taxes part of the statement is subject to a fair amount of resistance. This may be the result of activist movements that claim the government does not actually have the authority to levy taxes or because so many people go to such great lengths to avoid them. Death, on the other hand, is still universally believed to be inevitable, and, with it, all of the unpleasant stages and symptoms of aging.

While few argue that death can be escaped, there are growing numbers of people, professionals included, challenging the belief that aging is something we have no control over. This has nothing to do with magical fountains or deals made with the devil, like the Oscar Wilde novel in which Dorian Gray remained young while his portrait aged instead. Today, we are using cutting-edge science and research focused on reversing the effects of aging caused by a wide range of contributors, some of the more common being stress, environmental factors, weight, smoking, alcohol consumption, poor diet and DNA damage.

Studies on the Aging process

Particularly promising, researchers at the University of New South Wales (UNSW) believe that they have discovered a way to reverse the effects of aging by improving the ability of DNA to repair damage. As we get older, the body’s DNA is constantly undergoing damage and repair but, the older we get, the less efficient the repair part of the process is. The UNSW team has identified a substance that, when enhanced, restores the DNA’s former level of ability to make repairs. This research has generated a lot of excitement, including with the folks at NASA who are always working on better ways to keep the astronauts healthy during extended periods of time in space, where the effects of aging are dramatically exaggerated.

The UNSW study is just one of many programs working on the issue of slowing aging and reversing what we have always assumed to be the inevitable consequences of growing older. It simply isn’t true anymore that we have to accept limitations and decreased quality of life. Traditional medicine has done a good job of keeping us alive longer, but what is the point if we do so without being able to enjoy those extra years? The young do not have exclusive rights to good health. Don’t you owe it to yourself to find out just what is available to make you feel, act and look your best?

The Southern California Center for Anti-Aging focuses on the practice of advanced, preventive and regenerative medicine. We strongly believe preventive health should be customized to the individual  in testing and correcting  any chemical, nutritional and hormonal imbalances in the body. Therapy can help with creating the foundation for a healthier and happier life. Getting the body into balance is key to maintaining health. At our clinic, a program will be designed for each patient which might included but not limited to:

• Weight management
• Nutritional counselling
• Vitamin and mineral supplementation
• Exercise
• Detoxification
• Hormone balancing and stress management

Conclusion:

So is aging inevitable? Well, the short answer is yes. Humans have yet to find a real life fountain of youth or defy the restrictions of our mortality. This is probably a good thing. That being said, we have learned how to slow down the inevitable and add quality to our years. To learn more about our programs or if you have questions about any of our services, take advantage of our Free Consultation by filling out our convenient online form below.

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